… GSK-3 plays a key role in the enhanced AMPA throughput model underlying ketamine’s
rapid antidepressant … to involve AMPA receptor activation potentially mediated by GSK-3, with …

… -aspartate (NMDA) receptor antagonist ketamine fulfills some … GSK3 is a feasible target for
antidepressant effects because … trafficking of AMPA receptors were regulated by GSK3. Wild-…

… that the NMDA receptor may be a useful target for antidepressant … , ketamine can enhance
AMPA receptor throughput. In … that blocks GSK-3 phosphorylation did not respond to ketamine …

… GSK-3: a key regulatory target for ketamine's rapid antidepressant effects mediated by
enhanced AMPA to NMDA throughput. Bipolar Disord 2016; 18: 702–705, doi: 10.1111/bdi.12452…

… downstream-related targets associated with the regulation of rapid … by enhancing AMPA
relative to NMDA throughput in critical … Similarly, ketamine inhibited brain GSK-3 expression, and …

… The aim of this study was to summarize and highlight the … non-NMDA-mediated affects
of ketamine are summarized in … , AMPA was found to be an essential element in mediating …

… the cytosol to the nucleus and transcribe target genes (112). … of GSK-3 attenuated ketamine's
psychotomimetic-like effects (… AMPA receptor activation as a primary mediator of NMDA …

… allow ketamine-like rapid antidepressant effects by targeting … GSK-3 is required for the rapid
antidepressant-like effects of … Ketamine-inhibition of GSK-3 could occur via AMPA receptor …

… activation of AMPA receptors, which trigger mammalian target of … suggests that ketamine
act through regulation of brain-… ketamine enantiomers and metabolites to NMDA-R or AMPA-…

… neurotransmitters, neuromodulatory regulators, or from a trigger … , ketamine administration
also increases the AMPA to NMDA … -95, the target of GSK-3 that would promote AMPA-GluA1 …